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Among the participants treated with orforglipron in cohort 1, four participants had increased ALT levels greater than or equal to three times the upper limit of normal (ULN) and one participant in cohort 2 and one participant in the placebo group for both cohorts 1 and 2 experienced this elevation in ALT (Extended Data Table 3)
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doi: 10.1002/sim.3697 37 CohenJ